by Merritt Melancon, Mark Brown, Michael Strand and Kevin VogelUniversity of Georgia entomologists have unlocked one of the hormonal mechanisms that allow mosquitoes to produce eggs. Many hormones, including OEH and ILP, act through receptors on the surface of cells. In 2008, study co-authors Mark Brown, a professor of entomology, and Michael Strand, a Regent’s Professor, characterized the receptor for ILP in mosquitoes, which helped reveal many details about its role in egg formation. OEH plays an equally important role in female reproduction, but its receptor was more difficult to identify. “From previous work, we knew that the fruit fly Drosophila melanogaster does not produce OEH. A different group of fruit flies, including Drosophila mojavensis—as well as all mosquitoes we had genomes for—do have OEH,” said the study’s lead author Kevin Vogel, a postdoctoral fellow also in the College of Agricultural and Environmental Sciences’ entomology department. “Most hormones bind a single receptor, so we hypothesized that an OEH receptor should be found in mosquito genomes as well as Drosophila mojavensis, but not in the genome of Drosophila melanogaster.” By targeting the gene encoding the receptor, the authors found that disabling its expression inhibited the mosquitoes’ ability to produce eggs after a blood meal. The model for this research is the yellow fever mosquito, Aedes aegypti. Females have to consume a blood meal before they are able to produce a batch of eggs. The blood meal triggers the mosquito’s brain to release two hormones, an insulin-like peptide known as ILP and an ovary ecdysteroid-ogenic hormone known as OEH, which activate processes in the female mosquito that result in mature eggs. “This receptor fills a major gap in our understanding of the regulation of mosquito reproduction,” Strand said. “Going forward, we are well positioned to better characterize the steps leading to egg production and potentially identify points at which we can disrupt reproduction and control mosquito populations.” For more information on the UGA department of entomology, see www.ent.uga.edu. The results provide insight into how reproduction is regulated in female mosquitoes, which transmit agents that cause malaria and other diseases in humans and domestic animals. Their work was published in the April edition of the Proceedings of the National Academy of Sciences. The study is available online at www.pnas.org/content/early/2015/04/02/1501814112. Research reported in this release was supported by the National Institutes of Health under grant numbers R01AI033108 to Brown and Strand and F32GM109750 to Vogel. By identifying and comparing the sequences of more than 400 receptors in the genomes of two fruit flies and three mosquito species, they identified a single gene for a receptor with an unknown function within the species distribution they expected.
Sign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York A 22-year-old North Amityville woman was killed in a hit-and-run crash in North Lindenhurst early Friday morning, Suffolk County police said.Christina Ramdas was in the westbound lane of Route 109 when she was struck by a westbound vehicle east of Wellwood Avenue at 3:30 a.m., police said.The vehicle fled the scene, police said. The victim was pronounced dead at the scene.Vehicular Crime Unit detectives are continuing the investigation and ask anyone who may have witnessed this crash or has any information about the incident to call them at 631-852-6555 or call anonymously to Crime Stoppers at 1-800-220-TIPS FREE. All calls will be kept confidential.
Sign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York With rumors spreading from the shop floor to the newsroom, Newsday brass confirmed to staffers that the company is indeed considering big moves that will change how its been run for decades.To cut costs, Newsday is reportedly in talks with The New York Times to use the Gray Lady’s Queens printing plant and have The Times’ drivers distribute Newsday to Long Island. That would result in layoffs for about 100 of Newsday’s unionized employees. The Island’s lone daily newspaper may also move from its longtime Melville digs.“We are in the early stages of conversations with the union leadership about exploring possible changes to our business,” says Newsday spokeswoman Kim Grabina-Como, declining to discuss details.The move comes as Newsday, which Agility PR Solutions says is the sixth largest newspaper in the nation, has seen daily print circulation drop to less than 175,000, according to the latest Alliance for Audited Media report. Newsday claims its currentweekly combined print and digital audience on LI totals 1,131,193.As co-publishers Debby Krenek and Ed Bushey described in their Nov. 3 email to staffers, Newsday “would get out of the business of printing and distributing our products, and instead focus our resources and investments on content, audience and sales. It would also enable us to ultimately relocate to a more cost-effective and up-to-date office space.”Meanwhile, adding to the pressure, union contracts expired on Dec. 31. Negotiations, which had gotten underway just before the holidays, produced a tentative deal early in January, according to Mike LaSpina, president of Local 406, Graphic Communications Conference of the International Brotherhood of Teamsters, which represents Newsday’s contract employees.“I think it’s a good package,” LaSpina told the Press, but he declined to discuss any details until the general membership had seen it. He was hoping to hold the ratification vote on Jan. 20.LaSpina said that renewing the contract was his priority, but he knew that management was considering making some big moves in the coming months.“They did make me aware that they are looking into this,” LaSpina says. “I’m pretty comfortable we’ll get a deal.”Severance packages for the drivers and pressmen — LaSpina said that there were about 50 workers in each category — could eventually wind up on the table along with other issues, such as benefits and wages. No reporters or editors are on the chopping block at this point.“If that’s going to happen, I’ll try to negotiate a good deal,” says LaSpina.He wouldn’t say whether he’s been in contact with his counterparts at The Times. Nor would The Times discuss what’s afoot. Newsday scribes tried to take the news in stride.“Most of the drivers and pressmen are in their 60s and they’re more than ready to retire,” says one veteran journalist who spoke on the condition of anonymity. “The young reporters want to trust management but those of us who’ve been at the paper for a long time are worried. Nobody knows what’s going to happen.”Adding to the pressure is that Newsday’s lease with Tronc, formerly the Chicago-based Tribune Company that used to own the paper, is up July 31. The Newsday Media Group — three-quarters owned by Pat Dolan and his dad Charles and the remainder owned by Altice USA, part of a European telecom giant that had bought Cablevision from the Dolans in 2016 — reportedly pays an estimated $11 million in annual rent for the Melville property.Currently, the company occupies 300,000 square feet at 235 Pinelawn Rd. Long Island Business News reports management is considering leasing commercial space a third the size somewhere on the Route 110 corridor. It would be only the fourth time the paper has moved in its 78 years in business.Alicia Patterson, Newsday’s founder, originally set up shop at a former car dealership in downtown Hempstead when the first edition rolled off the presses in September 1940. Seven years later, the paper began expanding to a Garden City location. Then in ’77, Newsday, owned by the Los Angeles-based Times Mirror company, paid a local family of farmers $2 million for the 33-acre field that became the paper’s headquarters for the past 41 years.So now Newsday management, whose property gave its top executive suites vast views of Pinelawn National Cemetery across the street, hopes to stay alive in another part of town and avoid the fate of so many newspapers in the country that have already gone to their graves.
Dixies Federal Credit Union President and CEO Scott Eagerton is poised to testify for NAFCU and the credit union industry this afternoon during a House Small Business Subcommittee hearing on the impact of the Dodd-Frank Act on small businesses and financial institutions.Eagerton, whose credit union is headquartered in Darlington, S.C., is testifying before the House Small Business Subcommittee on Economic Growth, Tax and Capital Access, which is chaired by Rep. Tom Rice, R-S.C. The hearing is titled “Financing Main Street: How Dodd-Frank is Crippling Small Lenders and Access to Capital.”The NAFCU witness will discuss the tidal wave of new rules under Dodd-Frank and its “profound” impact on all credit unions and their ability to serve members.Eagerton’s testimony will focus specifically on credit unions’ growing regulatory burden under rules implemented by the CFPB, NCUA’s examination cycles, regulatory costs vs. benefits, NAFCU’s Top Ten rules targeted for elimination or improvement, proposals to ease statutory member business lending limits and more. continue reading » 12SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr
US President Donald Trump has meanwhile rejected the traditional presidential role of healer in the crisis.He has vowed to order a military crackdown on the once-in-a-generation widespread violent protests and has rejected criticism over his use of force to break up a peaceful rally.The statement from the UN rights office Wednesday pointed to “credible reports of unnecessary and disproportionate use of force by law enforcement officers” during the protests. The UN rights chief on Wednesday decried “structural racism” in the United States, and voiced alarm at the “unprecedented assault” on journalists covering protests across the country after George Floyd’s death in custody.Michelle Bachelet insisted that the grievances at the heart of the protests that have erupted in hundreds of US cities needed to be heard and addressed if the country was to move forward.”The voices calling for an end to the killings of unarmed African Americans need to be heard,” she said in a statement. “The voices calling for an end to police violence need to be heard. And the voices calling for an end to the endemic and structural racism that blights US society need to be heard.” Her comments came as thousands across the United States defied curfews for another night of rallies against police racism following the death of Floyd, an unarmed African American who stopped breathing as a police officer was filmed kneeling on his neck.Bachelet stressed the need for clear and constructive leadership to bring the country through the crisis. “Especially during a crisis, a country needs its leaders to condemn racism unequivocally; for them to reflect on what has driven people to boiling point; to listen and learn; and to take actions that truly tackle inequalities,” she said. ‘Unprecedented assault on journalists’ Tear gas and rubber bullets, as well as pepper balls have been fired at demonstrators and journalists “who did not pose an imminent threat of serious injury”, it said.Bachelet voiced particular alarm at reports that at least 200 journalists had been attacked or arrested while covering the protests, despite having press credentials clearly visible.”What has been happening is an unprecedented assault on journalists,” she said, pointing out that “in some cases they have been attacked or even arrested while on air.””It is all the more shocking given that freedom of expression and of the media are fundamental principles in the US, central to the country’s identity,” the UN High Commissioner for Human Rights said.”Reporters must be able to do their important work free from attacks or repression.”Bachelet also called on the protesters to refrain from violence, lamenting that several people, including a federal law enforcement agent, had died in the unrest, while dozens had been injured and numerous properties destroyed.”Violence, looting and the destruction of property and neighborhoods won’t solve the problem of police brutality and entrenched discrimination,” she said.And she voiced deep concern at statements seeking to label protesters as terrorists.”There can be no doubt as to what or who is ‘behind’ these protests,” Bachelet said, pointing out that “we have seen thousands upon thousands of peaceful protesters, of diverse backgrounds, taking to the streets to demand their rights and to call for change.”She acknowledged that “structural racism and police violence” are found across the world.But she warned that “the anger we have seen in the US, erupting as COVID-19 exposes glaring inequalities in society, shows why far-reaching reforms and inclusive dialogue are needed there to break the cycle of impunity for unlawful killings by police and racial bias in policing.” Topics :
Three homes near a national parkAs of last weekend all boaties are free to enjoy the waterways once again provided they follow social distancing rules, ie stay within 50 kilometres of their home, practice social distancing and are only joined by people they live with, or one other person. State border restrictions, however, are still in place, even on the water. If you own a boat or jet-ski, or are thinking of buying one, but want the convenience and accessibility of a private mooring place, these properties with a pontoon offer direct access to a life on the water. 53 Rosecliffe Street, Highgate HillEnjoy lazy days pootling up and down the Brisbane river from the house at 53 Rosecliffe Street, Highgate Hill. The four-bedroom 1920s home presents an opportunity for families and investors seeking an entry-level riverfront property. With traditional Queenslander interiors, the house oozes character, which extends outside to where there is a large timber deck. Landscaped gardens lead down to the edge of the river and a private pontoon. If you haven’t bought your own boat yet, the buyers of this house can catch the CityCat from the West End Ferry Terminal, which is only a short drive away. More from newsParks and wildlife the new lust-haves post coronavirus9 hours agoNoosa’s best beachfront penthouse is about to hit the market9 hours ago53 Rosecliffe Street, Highgate Hill has traditional Queenslander interiors.The house is open to offers through Sarah Hackett of Place Estate Agency.Farther up the coast at 6 Rainbow Lane, Pelican Waters, is an award-winning architecturally designed house with 67m water frontage and a 14m pontoon beside which you can moor a small yacht. The pontoon allows the homeowners water access to Pumicestone Passage and Caloundra heads. This house is situated on a large 1180sqm block and its double-storey layout features six bedrooms, most of which have water views. Water is a theme throughout property, which you enter over a boardwalk and which has a private man-made beach, several swimming pools and ponds and, inside, a 1000 litre marine aquarium. Interested parties can contact the selling agent, Jackie Dalton and Lucas Jefferies at Henzells Caloundra. 47 Longman Terrace, Chelmer.Finally, at 47 Longman Terrace, Chelmer, the recreational options are many and include large entertaining areas, a heated pool and spa, gymnasium, sauna and massage room, plus a games room and cellars. At the end of the landscaped gardens, however, lies a 12m pontoon, perfect for a boat or other leisure craft. The five-bedroom home on a 1,518sqm block is just 600m to Chelmer train station, a walk to Indooroopilly Shoppingtown and a 20-minute drive to Brisbane’s CBD. Offers are being received through Patrick or Jack Dixon of Dixon Estate Agency. 6 Rainbow Lane, Pelican WatersQueensland’s waterways are abuzz with recreational boaters and jet-skiers this week after the state government agreed to relax the COVID-19 rules on state waterways.In April the government announced recreational boating would be heavily restricted in a bid to slow the spread of coronavirus. Confusion reigned after Maritime Safety Queensland advised recreational boating was off-limits unless it was for essential travel before the Department of Transport and Main Roads clarified that boaties could also still head out to fish for food.MORE Buy and apartment, get a boat
South Korean shipping company KSS Line placed an order for the construction of a new class 84,000 cbm Very Large Gas Carrier (VLGC) at compatriot Hyundai Heavy Industries.This is the fifth VLGC order at the yard. All five VLGCs are scheduled for delivery in 2021.Once delivered, the LPG carrier is scheduled to enter into a KRW 155.5 billion long-term transportation contract with BGN Group, a European-based energy company, for seven years.The construction order is estimated to be worth USD 77.9 million.The gas carrier pertains to the same series of 84,000 cbm carriers ordered last year.The ships will be fitted with scrubbers to meet the IMO sulphur 2020 regulation.Based on the data from VesselsValue, the company has 21 live vessels in its fleet, including 16 LPG carriers with the latest order.World Maritime News Staff
Canadian oil and gas company Husky Energy has decided to cut its 2020 capital spending by $900 million in upstream spending and an additional $100 million in additional measures. Under the new plan, Husky has decided to delay the development of an oilfield located offshore China as well as development of a natural gas field offshore Indonesia.Husky said on Thursday it is taking a series of actions to fortify its business in response to challenging global market conditions.With these initiatives Husky is looking maintain the strength of its balance sheet while protecting value in an extended low commodity price environment.“Husky has three important advantages: a strong balance sheet, an Integrated Corridor which includes a sizeable downstream and midstream segment, and Offshore operations that include long-term gas contracts in the Asia Pacific region not linked to the price of oil,” said CEO Rob Peabody.Given current market conditions, Husky will start the reduction, or shut-in, of production where it is cash negative on a variable cost basis at current prices.The company’s total liquidity is $4.9 billion, comprised of $1.4 billion in cash and $3.5 billion in unused credit facilities. In line with its committed credit facilities, Husky is required to maintain debt to capital of no more than 65%, and is well below this threshold with a ratio of 27% with no long-term debt maturities until 2022.The company has revised its capital investment guidance in Upstream from $2.6 billion – $2.8 billion to $1.75 billion – $1.9 billion.The company’s total investment guidance was reduced from $3.2 billion – $3.4 billion to $2.3 billion – $2.5 billion.Total Upstream Production (mboe/day) has been revised from 295 – 310 to to 275 – 300.According to Husky, investment in resource plays and conventional heavy oil projects in Western Canada has been halted, with a focus on optimizing existing production and lowering costs. Furthermore, drilling of sustaining pads at all thermal operations has been suspended and Lloydminster thermal projects scheduled to be delivered beyond 2020 have been deferred and will be reconsidered as market conditions improve.In the Asia Pacific region, the development of the Block 15/33 oil field offshore China has been deferred by a year. In Indonesia, development of the MDA-MBH natural gas field has been deferred.The Liuhua 29-1 field at the Liwan Gas Project is being advanced as planned, with first production expected by the end of 2020.The company said it continues to review further capital adjustments in response to the current market environment.Additional cost reduction initiatives totalling approximately $100 million in 2020 will include a reduction in well servicing activities on uneconomic production, and a halt in exploration activity.
Promoted ContentWhy Go Veg? 7 Reasons To Do ThisWhich Country Is The Most Romantic In The World?Top 10 Most Romantic Nations In The World7 Things That Actually Ruin Your Phone18 Cities With Neverending Tourist-FlowBirds Enjoy Living In A Gallery Space Created For ThemThis Guy Photoshopped Himself Into Celeb Pics And It’s Hysterical7 Non-Obvious Things That Damage Your PhoneCouples Who Celebrated Their Union In A Unique, Unforgettable Way6 Extreme Facts About HurricanesThe Best Cars Of All Time6 Ridiculous Health Myths That Are Actually True “Today Aston Villa was fighting with all they had and it makes life uncomfortable. It was not a brilliant performance but it was a good performance that gets us three points.” Klopp has insisted he will not dish out appearances “like Christmas presents” in the final month of the campaign as his side eye a record points tally in English top-flight history. Liverpool moved onto 89 points with a further 15 still up for grabs to beat City’s record of 100 from two seasons ago. Loading… The Kop at Anfield was quiet in Liverpool’s first home match since becoming Premier League champions In front of an empty Anfield, the hosts struggled to summon their best with the big prize already won and just re-writing the record books to play for.Villa, by contrast, are still desperate for points in their battle to beat the drop and Dean Smith’s men were left to rue not taking their chances on the counter-attack early in the second half as their winless streak stretched to 10 games.“I don’t want to be a valiant loser because we are running out of games,” said Smith.“To out-shoot Liverpool at home at Anfield, in terms of efforts on goal is excellent, but need to take our opportunities. We never found the quality in the final third they did.”Pepe Reina was recalled in the Villa goal on his return to Anfield where he spent nine years as a Liverpool player, but the Spaniard barely had a save of note to make before half-time as Liverpool struggled to break Villa down.Indeed, it was Alisson Becker who was the busier goalkeeper as the Brazilian was forced to parry shots from Douglas Luiz, Jack Grealish and Anwar El Ghazi.Klopp was forced into introducing Jordan Henderson, Georginio Wijnaldum and Roberto Firmino to try and summon a response from his side in the final half hour.The triple substitution quickly made a difference when Naby Keita picked out Mane to sweep home his 20th goal of the season.Read Also: Video: Che Adams nets 40-yard screamer to open EPL account“I didn’t thank him for bringing the three subs on,” added Smith. “That strengthened them.”Reina was finally forced into a fine save as he dived to his left to deny Firmino his first goal at Anfield this season.Another substitute made the game safe a minute from time as 19-year-old Jones saw his effort deflect past the helpless Reina before Alisson produced another stunning save at the other end to deny Grealish a consolation.FacebookTwitterWhatsAppEmail分享 Jurgen Klopp said Liverpool’s ability to grind out wins when not at their best has been a hallmark of the champions this season after Sadio Mane and Curtis Jones struck in the final 20 minutes to beat struggling Aston Villa 2-0 on Sunday. After a 4-0 humbling at the hands of Manchester City in their first match as Premier League champions on Thursday, Klopp’s men again failed to hit the heights that made them runaway leaders before a three-month hiatus due to the coronavirus pandemic. But Mane’s sweet strike off the underside of the bar and Jones’s deflected effort kept up a run of 24 consecutive league wins at Anfield for the Reds and left Villa still languishing in the bottom three. “We are where we are because we win difficult games,” said Klopp.Advertisement
FOOD for the Poor (Guyana) Incorporated (FFP) recently donated a quantity of cricketing gear including bats, balls and stumps to the Malteenoes Sports Club (MSC) youth cricket academy which started on Monday, August 22, at its Thomas Lands facility.Joel Alleyne, a member of the MSC senior cricket team, thanked FFP for the donation which he said would go a long way in assisting the youngsters in the programme in their cricket development.In his remarks, Public Relations Manager of FFP Wayne Hamilton, said that FFP was committed to assisting in the development of all sports in Guyana as far as possible.He further stated that he hoped the youths would take advantage of the opportunities afforded them in the programme and listen carefully to the coaches and facilitators, and strive to enhance the further development of the sport in our country.